Defying Gravity is a multi-nationally produced space travel television drama series, first aired on August 2, 2009 on ABC and CTV and canceled in the fall of 2009. Set in the year 2052, the series follows eight astronauts (four women and four men) from four countries on a six-year space mission through the Solar System, during which they are monitored from Earth via a real-time communication system. The series was pitched to networks as "Grey's Anatomy in space". On October 29, 2009 the show's creator James Parriott revealed how the show would have progressed in response to questions in a follow up interview about the show.

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